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(PubMed) Gut Health Champion: Explore BPC-157s impact on gastrointestinal health, from battling leaky gut and IBS to addressing Crohns disease, opening doors to new therapeutic approaches
70 This evolutionary dynamic has been demonstrated in NSCLC and melanoma treated with PD-1 blockade and explains why tumors with high mutational burden may still acquire rapid resistance to immunotherapy
Thymosin beta 4 is also one of few compounds in this class with genuine randomised controlled human data, though in a topical ophthalmic formulation rather than a systemic one, RGN-259 eye drops having been evaluated in placebo-controlled Phase 2 and Phase 3 trials (Sosne et al., Cornea 2015 and Int J Mol Sci 2023)
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