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Gastrointestinal Adverse Events Of the adverse effects reported during GLP-1 RA clinical trials, gastrointestinal symptoms were the most frequent, with nausea and diarrhea very common, and vomiting, constipation, abdominal pain, and dyspepsia considered to be relatively common [97]

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The antioxidant defense system of melanocytes, when exposed to daily external prooxidant factors, including UV, has difficulty maintaining redox balance, which indicates the need for additional protective strategies

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