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Nair KS (1987) Hyperglucagonemia increases resting metabolic rate in man during insulin deficiency
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For composite kidney outcomes, the HR was 0.52 (95% CI 0.330.83) with SGLT2is and 0.70 (95% CI 0.590.83) without SGLT2is ( P -value for interaction 0.38) (Table 3)
A low-fibre diet can lead to harder stools, requiring more effort to pass, which increases pressure on the rectal veins
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