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The clinical starting dose of semaglutide is 0.25 mg weekly, ramping up to 1.0 mg or 2.4 mg (for Wegovy) over several months

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(The UK Medicines regulator (MHRA) has confirmed in its 2026 recommendation that the only person making fluid transition through the spectrum of GLP-1 medicines will be your prescriber.) Mounjaro to Wegovy Dose Conversion: What the Evidence Says It lacks a peer-reviewed conversion guide to refer to specifically because there have been no direct clinical trials comparing Mounjaro doses to Wegovy doses in a switching context

Although direct preclinical evidence remains limited, this represents a promising direction for future investigation