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Kidney injury appears only as a secondary effect of dehydration from severe gut upset. Anti-drug antibodies form in roughly half to two-thirds of users but do not affect clearance, weight, or blood sugar. Benefits that look like side effects Tirzepatide lowers uric acid (about -0.7 to -1.0 mg/dL, mostly through weight loss) and lowers blood pressure
Chang S-H, Chang C-H, Yang M-C, et al
However, the finding was considered secondary to the reduction of blood pressure rather than a direct effect of the drug on the RAAS
Statin Toxicity
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