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In the United States, Tirzepatide has recently gained approval for treating moderate to severe obstructive sleep apnea in adults with obesity [119] as well as semaglutide use for metabolic dysfunctionassociated steatohepatitis (MASH) with moderatetoadvanced fibrosis [120]
The method can assay GSH in whole blood, plasma, serum, lung lavage fluid, cerebrospinal fluid, urine, tissues and cell extracts and can be extended for drug discovery/pharmacology and toxicology protocols to study the effects of drugs and toxic compounds on glutathione metabolism
Annex I summary of product characteristics
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