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The biosynthesis of S-adenosylmethionine during homocysteine metabolism from methionine further activates DNA methyltransferases, leading to alterations in the DNA methylation status of various genes implicated in mitochondrial homeostasis [63]
doi:10.1016/0014-5793(88)80509-X PMID: 3169264 4
That translates to roughly 58 pounds for someone starting at 240 pounds
Nicotinamide Adenine Dinucleotide in Aging Biology
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