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Rigorous scientific studies definitively proving the effectiveness of these injections for weight loss are scarce

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By 48 weeks, a secondary endpoint, the mean percentage change in weight was 8.7% in the 1-mg group, 17.1% in the combined 4-mg group, 22.8% in the combined 8-mg group, and 24.2% in the 12-mg group, with a mean loss of just 2.1% in the placebo group