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Research highlights NAD+ Increased cellular NAD+ via nicotinamide pool NNMT Enzyme overexpressed in obese adipose tissue Anti-adip Reduced lipid accumulation and adipocyte differentiation SIRT1 Downstream sirtuin activation via NAD+ elevation Research notes Adipocyte research: In vitro models show reduced lipid accumulation and pre-adipocyte differentiation upon NNMT inhibition
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10.1016/j.tox.2004.05.008 Toxicology 251 KohS
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