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Chugai's medicinal chemistry effort identified a series of non-peptide compounds that activated the GLP-1 receptor with nanomolar potency through a previously unrecognized binding pocket
These nasal sprays are studied in research for their ability to stimulate growth hormone release and related signaling pathways in test models
Fink-Jensen A, Wrtwein G, Klausen MK, Holst JJ, Hartmann B, Thomsen M, et al
Recently, Naidu et al [80] demonstrated that ascorbyl stearate inhibited cell proliferation by interfering with cell cycle, reversed the phenotype and induced apoptosis by modulation of insulin-like growth factor 1-receptor expression in human brain tumor glioblastoma (T98G) cells
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