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In this group, circulating TMAO was associated with reduced values of estimated glomerular filtration rate (eGFR, Spearman rho = 0.124, pFDR = 0.06) and higher fasting concentrations of uric acid (rho = 0.114, pFDR = 0.09) after adjustment for age, sex, country of recruitment (demographics thereafter) and body mass index (BMI) (Supplementary Fig
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GLP-1R immunostaining was intensely positive in small and medium-sized neurons in human DRG, and in human and rat DRG cultured neurons
Tirzepatide (Zepbound/Mounjaro) produced roughly 21 to 23 percent in the SURMOUNT trials at the highest dose
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