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In a randomized, placebo-controlled trial in 1,374 participants who had colonoscopic removal of at least one colorectal adenoma (the Selenium and Celecoxib trial), selenium supplementation (200 g/day with selenized yeast) for a median of 33 months had no effect on colorectal adenoma recurrence (88)
doi: 10.1016/S1474-4422(05)70023-5 68 GiovannoniG.HawkesC
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