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When toxic exposure, gut-derived inflammation, low zinc, oxidative stress, low SAM or elevated SAH exceed the livers metabolic reserve, detoxification may become less efficient and contribute to fatigue, brain fog, mood symptoms and toxic overload
Some papers have suggested that methylene blue may not work well for aniline-induced methemoglobinemia because of decreased erythrocytic uptake of methylene blue in the face of the phenylhydroxylamine, but we have found continuous infusions to be effective for aniline toxicity
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