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This adaptation persists after stopping GLP-1 medications and contributes to weight regain

The most pronounced improvements in BC were observed after 3 and 6 months of treatment, whereas after 12 months these beneficial effects tended to diminish

03 Draw bacteriostatic water Pull the planned volume of BAC water (commonly 1-2 mL for a 1 mg vial) into a sterile mixing syringe

Preclinical models indicate that GLP-1 receptor activation can influence the gut-brain axis as well as the hypothalamic-pituitary-adrenal (HPA) axis, with possible implications for stress regulation and energy homeostasis[11]