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Most patients should aim for sufficient fluid intake throughout the day rather than consumed in large amounts at once
When to seek medical advice: Contact your GP for persistent but non-urgent symptoms Use NHS 111 for urgent concerns Attend A&E or call 999 for: Persistent vomiting preventing adequate fluid intake Signs of dehydration (dark urine, dizziness, dry mouth, decreased urination) Severe abdominal pain, particularly if radiating to the back (possible pancreatitis) Upper right abdominal pain with fever or jaundice (possible gallbladder issues) Severe allergic reaction Inability to tolerate any food or fluids for more than 24 hours Your prescribing clinician may consider delaying dose escalation or temporarily reducing the dose if side effects are particularly troublesome, as outlined in the SmPC
The Precision Peptide Genetic Test identifies predispositions in peptide-pathway genes but does not predict exact medication response
The Salehpour 2019 study (80 women, 3,000 mg/day, 12 weeks) reported no relevant side effects
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