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Reactive oxygen species-mediated signaling during abiotic stress

Additional known effects include cholelithiasis (related to rapid weight loss), a modest heart rate increase of 2-4 bpm, and a boxed warning for thyroid C-cell tumors based on rodent data

10.1002/nbm.2772 NMR Biomed

162 TMAO may accelerate the progression or rupture of abdominal aortic aneurysm by inducing VSMC apoptosis through the activation of PERK-mediated UPR