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Researchers dont know precisely why semaglutide and constipation can often go hand-in-hand, but they theorize its related to how the medication works on your digestive system: It slows your digestion: Semaglutide is a glucagon-like peptide-1 receptor ( GLP-1 ) agonist that delays gastric emptying the movement of food from your stomach into your intestines

Tirzepatide also supports healthier blood sugar levels, which can help reduce inflammation, improve energy, and support overall metabolic health

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The peptide portion contains three amino acidsglycine, histidine, and lysinewhile the histidine residue contributes strongly to copper coordination