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doi: 10.1007/s00432-009-0574-8 126 KatohYKatohM
A 2024 review in BioImpacts synthesizing the topical GHK-Cu evidence concluded that the peptide has consistent anti-wrinkle and skin-rejuvenating activity in human studies, though formulation and delivery remain ongoing challenges [5]
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Brachycephalic breeds (eg, pugs, Boston terriers, English and French bulldogs) and Shar-peis have excessive skin folds, especially on the face, that can trap moisture and predispose these breeds to fungal or bacterial skin infections
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