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J BiolChem
The mechanisms by which LA reduces liver fat content in HFD animals may be related to suppressing oxidative stress and lipid peroxidation, improving mitochondrial dysfunction, inhibiting insulin resistance, and regulating some related factors or genes (such as ROS-scavenging enzyme genes) to inhibit excessive fat synthesis in the liver
These are typically mild and often decrease over time as the body adjusts to the medication
Available both as an injection and an oral pill, semaglutide functions by emulating GLP-1, a natural hormone that reduces appetite and encourages significant, durable weight loss
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