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Efpeglenatide (a modified exendin conjugated to human immunoglobulin-4 via a polyethylene glycol linker) has shown metabolic efficacy and cardiorenal benefits as a once-weekly subcutaneous injection during Phase 3 trials, but has yet to be progressed further [38]
Less beta-arrestin recruitment could mean less receptor desensitization over time
Yes, osmotic laxatives like polyethylene glycol (MiraLAX) and stool softeners like docusate (Colace) are safe to use with semaglutide injection and carry no known drug interactions
Her work has been published in Bon Apptit , Women
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