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Jastreboff AM, Aronne LJ, Ahmad NN, et al
Activating it (or in this case, increasing its expression and signaling capacity) triggers hormone-sensitive lipase, which begins breaking down stored triglycerides into free fatty acids and glycerol
People with severe malabsorption, pernicious anemia, or advanced deficiency may not respond adequately to oral supplements alone
Healthy, Evidence-Based Approaches to Weight Management in the UK NICE CG189 and NICE PH53 recommend calorie-controlled diet, regular physical activity, and behavioural support as the evidence-based cornerstones of weight management
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