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It is also used in glutamate-cysteine ligase regulation and Nrf2/ARE pathway work, where glutathione acts as the feedback inhibitor of its own synthesis (Lu, Biochimica et Biophysica Acta, 2013)
Preprint at bioRxiv (2021)
Thus, they demonstrated that Prx2 prevents metHb aggregation, and, probably acts as a chaperone for the denatured Hb [96]
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