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The proposed mechanisms behind BPC-157 center on four distinct biological processes, which are the formation of new blood vessels, the reorganization of the extracellular matrix, the proliferation of fibroblasts, and inflammatory regulation

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Controlled negative result: topical GHK-Cu gel on irradiated rat dorsal flaps showed no difference versus control in flap ischemia, vessel number/area or VEGF expression counter-evidence that the copper-tripeptide class is not uniformly effective even topically