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Clinical targets: Currently in Phase 2 and Phase 3 trials, Survodutide is being studied for obesity, type 2 diabetes, and metabolic dysfunction-associated steatohepatitis (MASH)

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It is an imbalanced agonist with GIPR potency close to native GIP but weaker GLP-1R affinity, and shows biased GLP-1R signaling, favoring cAMP over -arrestin recruitment

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But as a comment on my recent piece about energy drinks pointed out, there's much more in these beverages than just caffeine and water

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