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These results compare to all doses of mizagliflozin combined in all subjects dosed, compared with baseline, showing the glucose nadir was raised by 14.5 mg/dL (21%) (p=0.0.45), the glucose peak was lowered by -29.6 mg/dL (16%) (p=0.027), and the insulin peak was lowered by -161.8 IU/mL (43%) (p=0.012)
We postulate that boosting mitochondrial metabolism might be a potential therapeutic strategy to induce antidepressant effects
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