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The segmental duplications are observed in different chromosomes whereas tandem duplications occur in the same chromosome (Liu et al., 2011)
Safety and efficacy of vildagliptin versus placebo in patients with type 2 diabetes and moderate or severe renal impairment: a prospective 24-week randomized placebo-controlled trial
For how these effects fit into the receptor biology, discovery, and pipeline behind the class, see the wider view of GLP-1 and metabolic disease
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