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Finally, we examine potential BBB-based therapeutic strategies and targets

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The following primary antibodies were used: anti-FLAG M2 (F3165, Sigma-Aldrich/Merck), anti-C16orf70 (ab181987, Abcam), anti-WIPI2 (purified mouse IgG clone 2A2 from the Tooze lab), anti-HA (H3663, Sigma-Aldrich/Merck), anti-VDAC (D73D12, Cell Signaling Technology), anti-PDI (C81H6, Cell Signaling Technology), anti-PMP70 (P0497, Cell Signaling Technology), and anti-BCAS3 (ab71162, Abcam)