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The frequency of NAION in the analyses ranged from 0.07% to 0.24%
In the single-dose study, subjects received 10 mg oral semaglutide with 50 or 240 mL water while fasting, AUC 0-24h and C max were approximately 70% higher when dosed with 50 versus 240 mL water
doi:10.1186/s12967-025-06341-5 Console L, Scalise M, Mazza T, et al
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