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Athletes and biohackers pursuing musculoskeletal repair should understand that injectable use is now in a regulatory gray zone following the 2026 FDA Category 2 designation, making physician-supervised topical compounding the only currently legal route
Compounded medications are not approved or evaluated for safety, efficacy, or quality by the FDA
The affected area often appears red and inflamed, and the sores can take several days to heal
Tesamorelin has the strongest evidence for reducing visceral abdominal fat in adults with HIV-associated lipodystrophy, while GLP-1/GIP medications such as semaglutide and tirzepatide are generally stronger options for overall weight loss
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