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Exogenous GH suppresses pulsatility and results in negative feedback
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Before it can become routinely available in the UK, it must: demonstrate long-term safety and effectiveness in larger populations receive approval from the Medicines and Healthcare products Regulatory Agency (MHRA) undergo assessment by the National Institute for Health and Care Excellence (NICE) for NHS use become commercially available through licensed providers Timelines depend on the outcome of ongoing studies and regulatory review
This difference affects how long it circulates and how strongly it interacts with growth factor receptors in research settings
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