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The primary causes include: Autoimmune Response: The immune system attacks stomach cells that produce intrinsic factors, preventing vitamin B12 absorption
ADAMTS9, ADAM metallopeptidase with thrombospondin type 1 motif 9
Pros: Pharmaceutical-grade, FDA-registered facility production Third-party lab tested for purity and potency Hundreds of 5-star reviews from verified users Optional CurcuPrime version with enhanced curcumin 15% subscribe-and-save discount available Trusted in functional medicine and anti-aging circles Trial size available (30 capsules for $70) Cons: Mid-to-high pricing at $130 for 60 capsules No specialized absorption enhancers like SNAC Pure BPC-157 only (no synergistic ingredients in standard version) CurcuPrime version adds cost without clear added benefit More expensive than Paramount with similar stability Best for: Those who want a proven, medical-grade option from a peptide-specialist brand, especially if youre already working with a functional medicine practitioner
DOI: 10.1186/s13195-022-00961-5
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