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How They Work: The Science Behind Each Medication Understanding the mechanisms helps explain why Mounjaro might produce better results, though both work remarkably well
Going from 4 mg to 8 mg in one step is harder on the gut than two smaller increases with a 4-week interval between them
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Associations remained even after accounting for intervening progression to diabetes
A healthy weight loss is between 1-3 pounds per week, which means ideally you should lose between 4-12 pounds in a month on semaglutide, we aim for our patients to stay within this range
![Mechanism of action of GLP-1 [25]](https://www.researchgate.net/publication/256289222/figure/fig1/AS:614177232142337@1523442671231/Mechanism-of-action-of-GLP-1-25.png)
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