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AI and AI-assisted tools statement During the preparation of this manuscript, the AI tool ChatGPT (GPT-5, released 2025-08-07) was used to generate Figure 1 and the Graphical Abstract and to improve the readability and language of the manuscript
Melatonin signals circadian timing (when to sleep)
We use cyanocobalamin by default, the form of B12 with the longest clinical history, the most extensive research support, and the consistent potency needed for repeated treatments
K.SinghR
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