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Efficacy of liraglutide for weight loss among patients with type 2 diabetes: the SCALE Diabetes randomized clinical trial

Table 2 Major clinical outcomes after matching

Of note, the kinase activity of IGF-IR is not required for its nuclear translocation and activation of transcription [88]

In contrast, the metabolically impaired penumbra tissue may remain in a salvageable state if perfusion and cellular homeostasis are restored through appropriate therapeutic interventions [1, 3, 4]