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Clinicians working with patients who have compromised gut barrier function, often framed as increased intestinal permeability or "leaky gut," sometimes extend oral BPC-157 protocols to ten to twelve weeks given the chronicity of the underlying pathology
BRCA mutations, Lynch syndrome, Li-Fraumeni syndrome, and other hereditary cancer syndromes create environments where additional risk factors deserve careful consideration
While not dangerous, they indicate significant vascular reactivity and suggest the nitric oxide system is responding robustly to the peptide
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