It is administered as a subcutaneous injection once weekly, with available doses of 0.75 mg, 1.5 mg, 3 mg, and 4.5 mg (Table 1)
GLP-1 receptor agonist medications mimic the action of glucagon-like peptide 1 (GLP-1), a hormone secreted by your intestines when you eat
Science 292 : 727730 Urano F, Wang X, Bertolotti A, Zhang Y, Chung P, Harding HP and Ron D (2000) Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1
For Ozempic, treatment typically starts at 0.25 mg weekly, while Wegovy also begins at 0.25 mg weekly but follows a different escalation schedule to reach the maintenance dose of 2.4 mg