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In parallel, there is also an increase in Mbnl2 expression and a decrease in nSR100 activity (Supplementary Fig

Up to know, the majority of established and newly synthesized GST inhibitors have been primarily tested for their cytotoxic effect in cancer cell lines and mouse xenograft models, showing promising activities

Additionally, in vitro studies with pituitary cells suggest a similar increase in GH release upon exposure to DSIP, albeit with a notable decline at higher concentrations