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Upregulated hexokinase 2 expression induces the apoptosis of dopaminergic neurons by promoting lactate production in Parkinsons disease
In such an abundance of glucose, insulin also stimulates the synthesis of glycogen by phosphorylation of glycogen synthase kinase 3 (GSK3), which leads to dephosphorylation and activation of glycogen synthase (McManus et al., 2005)
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