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Furthermore, the redox activity of PDI, but not its chaperone function, rescued motor dysfunction and axonopathy in zebrafish models of ALS expressing mutant SOD1, together implying that PDI has an important role both in vitro and in vivo (Parakh et al., 2020)
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Cagrilintide has not been specifically studied for liver fat reduction, though any compound that produces significant weight loss will likely reduce liver fat as a secondary benefit
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