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The following medications are FDA-approved for long-term use for weight reduction: Orlistat (Xenical, Alli) Bupropion-naltrexone (Contrave) Phentermine-topiramate (Qsymia) Setmelanotide (Imcivree) Liraglutide (Saxenda) Semaglutide (Wegovy) Takeaway Tirzepatide (Zepbound) is the newest weight-loss drug approved by the U.S
The medication is not safe for pregnant and breastfeeding females and children
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PT-141 activates melanocortin receptors in the central nervous system
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