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Drugs that work purely by suppressing appetite tend to lose ground when the body fights back, lowering its own energy expenditure to defend a higher set point

Effect of liraglutide on ambulatory blood pressure in patients with hypertension and type 2 diabetes: A randomized, double-blind, placebo-controlled trial

For this reason, patients under semaglutide could benefit from this nutritional therapy, specifically those with more complicated metabolic profiles and who seek for substantial weight loss in the initial phase