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In some patients, inflammatory responses rather than direct infection may contribute to: Chest tightness Air hunger Mild hypoxia Nonproductive cough Some patients report worsening respiratory symptoms during Herxheimer reactions or later-stage illness

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Once inside the cell, enzymes can rapidly break down and process the S-acetyl-L-glutathione compound so that it can be rapidly absorbed by the body

A GST mutant in which four glutamine residues were replaced with asparagine (GST 4QN ) exhibited a glutathione binding affinity similar to that of wild-type GST and could be purified by glutathione affinity chromatography