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It is necessary to test a potential compound on animals before clinical studies
( Reference Dutta, Seirafi and Halpin 39 ) , although riboflavin deficiency alone did not affect the activities of GPx and GR and increased the content of glutathione in the liver, ethanol administration (which can exacerbate oxidative stress) significantly decreased the activities of these enzymes and the content of glutathione in the liver of riboflavin-deficient rats compared with those in the liver of the riboflavin-sufficient control rats
These data indicate that KL1 s phenotype is not due to background noise from the compound, the host cells or dead extracellular bacteria
Epidermal growth factor and the liver The EGF is a member of the growth factor family, and the activation of the EGF/EGFR axis has been extensively studied in various biological processes
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