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Research supports 1.2 to 1.6 grams per kilogram, with some experts recommending up to 2.0 grams per kilogram during active weight loss phases
Given 40-60% nasal bioavailability compared to 80-95% for injection, equivalent nasal doses would be approximately 400-1000mcg to achieve similar systemic levels
307 , C39C54 (2014)
While the factors underlying brain health and longevity discussed below are not exhaustive, they represent what appear to be the most quantifiable and targetable factors underlying neurodegenerative processes along the MCI-ADRD continuum
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