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Similarly, in mesangial cells, GLP-1 receptor agonists have been shown to suppress either high-glucose-induced or AGEs-induced pro-fibrotic signalling pathways, including NF-B activation and TGF-1 expression, leading to reduced ECM deposition [60,61], and to suppress their proliferation via AMPK activation [62]

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This informationcombined with your state's coverage criteria, your metabolic labs, and your treatment goalssupports a more nuanced, evidence-based conversation about whether compounded GLP-1 options, Medicaid coverage timelines, or a hybrid approach best serves your health needs

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