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Apr 2012;29(4):325-8
Cells 13, 1945
Key differences in bioavailability: Prescription injections: High bioavailability due to direct delivery into the bloodstream OTC oral supplements: Variable bioavailability due to gastrointestinal absorption factors Understanding the differences between prescription B12 injections and OTC supplements helps healthcare providers tailor treatments
Published in vitro work has characterized 5-Amino-1MQ as a competitive NNMT inhibitor with low micromolar potency against the recombinant enzyme, and as a cell-permeable agent that suppresses NNMT activity in cultured 3T3-L1 adipocytes at micromolar concentrations [1]
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