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Key Facts Although the drugs were first approved for Type 2 diabetes maintenance, they were approved for weight loss in recent years, and research has shown they cause significant results: Tirzepatide typically causes patients to lose an average of 22.5% of body fat, while semaglutide causes a 15% reduction
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We were not able to compare differences between drug type or source, though we have previously reported large reductions in subjective effects of alcohol in people taking tirzepatide 18
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