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12-Month Cost Comparison For one year of treatment at various price points: Mounjaro with insurance + savings card: approximately $300 ($25 12) Zepbound vials through LillyDirect: approximately $4,739 ($349 2 months + $499 10 months) Mounjaro with discount card: approximately $12,000 ($1,000 12) Mounjaro at retail: approximately $13,000 to $15,600 Compounded tirzepatide: approximately $4,188 ($349 12) 18-Month Cost Comparison For typical treatment duration: Mounjaro with insurance + savings card: approximately $450 Zepbound vials through LillyDirect: approximately $7,737 Mounjaro with discount card: approximately $18,000 Compounded tirzepatide: approximately $6,282 The Insurance Coverage Difference The cost difference between having insurance coverage versus not is dramatic