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At the conclusion of the STEP 1 trial, the average weight loss among the 1,961 participants averaged 14.9% of their initial body weight.[2] For example, if a participant started at 260 pounds and lost 14.9% of their body weight, they would have lost 38.7 pounds
What it does is restore the metabolic signaling environment that makes those inputs effective again
This is in line with what has been seen with other GLP-1 RAs [45]
Application of berberine on treating type 2 diabetes mellitus
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