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The concentration of the samples was quantified with 1 H NMR after filtration through celite
Add each solvent one by one: 10% DMSO 40% PEG300 5% Tween-80 45% Saline Solubility: 2.08 mg/mL (4.12 mM)
It is most often seen during the early stages of treatment or after dose increases, which is why gradual titration is a central part of the dosing strategy used in clinical studies
BLyS, also known as BAFF, is a B-cell activating factor of the tumor necrosis factor (TNF) family, while a proliferation-inducing ligand (April) is associated with the activation of mature B cells and plasma cell antibody secretion (Lee et al., 2021
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